Remapping Text in Sentence and Word Tasks to Aid Reading With Central Vision Loss
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age16+
SponsorUniversity of Minnesota
About this trial
Reading performance in patients with Central Vision Loss will be measured with and without missing text being remapped to different parts of the visual field in a variety of different reading tasks.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Dense bilateral scotomas of at least 2 deg diameter in each eye covering the fovea
Bivariate contour ellipse area (BCEA) of less than 10² is obtained in a simple fixation task
Disqualifiers
Neovascular AMD
Any history of visual disorders other than that causing the central vision loss.
Trial design
Design model
Parallel
Treatments tested in this trial
Personalised Remapping Training
BehavioralParticipants will receive training across multiple days with text being shifted in real time as it is being read from locations covered by scotoma to locations determined by personalization procedure .
RSVP personalized remappi
BehavioralParticipants will read one word at a time presented in rapid succession at fixation with text being shifted from scotoma locations to locations determined by personalization procedure.
Reading text in the wild with remapping
BehavioralParticipants will read short texts presented in natural scenes in virtual reality with text being shifted from scotoma locations to locations determined by personalization procedure.
Treatment groups
100 Participants
are divided into 3 treatment groupsGroup A: Perceptual LearningExperimental treatment 1 intervention
Group B: Rapid Serial Visual PresentationExperimental treatment 1 intervention
Group C: Reading in The WildExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Sentence reading speed
Time it took to read sentence in words per minute
Time frame
Measured on day 35, end of the Personalised Remapping Training in the 33 participants in the Perceptual Learning arm.2
Sentence reading accuracy
Percentage of correctly read words in sentence
Time frame
Measured on day 35, end of the Personalised Remapping Training in the 33 participants in the Perceptual Learning arm.3
Word reading speed: RSVP
Time taken to read each word
Time frame
Measured on day 21, end of the RSVP Remapping intervention in the 33 participants in the Rapid Serial Visual Presentation arm.4
Word recognition accuracy: RSVP
Percentage of words correctly read
Time frame
Measured on day 21, end of the RSVP Remapping intervention in the 33 participants in the Rapid Serial Visual Presentation arm.Sponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: