Repetitive Transcranial Magnetic Stimulation in Patients With Hemiplegic Stroke
ConditionStroke
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorDongtan Sacred Heart Hospital
About this trial
Stroke is one of the major causes of death in the World. Many stroke survivors may suffer from long-term sequelae of stroke such as hemiplegia. The effects of rehabilitation therapy are limited. The development of new treatment strategies is essential. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive method to stimulate the focal area of the brain for restoring brain function. The aim of this study is to investigate the therapeutic effect of rTMS on the motor recovery in patients with hemiplegic stroke.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
stroke patients with motor weakness
Medical research council (MRC) grade 0-4
More than 2 weeks after stroke onset
Age 18 years and older
Disqualifiers
History of previous symptomatic stroke
pregnant women
Persons with surgically or traumatically implanted foreign bodies such as a pacemaker, an implanted medication pump, a metal plate in the skull, or metal inside the skull or eyes (other than dental appliances or fillings), intracardiac lines that may pose a physical hazard during magnetic stimulation will also be excluded
Patients with history of seizure disorder or epilepsy
Trial design
Design model
Parallel
Treatments tested in this trial
Traditional Theta burst stimulation (TBS)
DeviceModified TBS rTMS
DeviceSham rTMS
Device
Treatment groups
48 Participants
are divided into 3 treatment groupsGroup A: Tradtional Theta burst stimulation (TBS) rTMSExperimental treatment 1 intervention
Group B: Modified TBS rTMSActive comparator 1 intervention
Group C: Sham rTMSSham comparator 1 intervention
Trial outcomes
Primary outcomes
1
Keyboard tapping test
Participants will be asked to tap a key of a computer keyboard as fast as possible in five seconds. They will be asked to do three times. We will measure the number of tapping. The primary outcome will be the averaged data of the numbers.This will be done before and after 5-day rTMS intervention.
Time frame
1 daySponsors and contacts
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Source ClinicalTrials.gov