Health TrialsbyHealthPanel

Residual Neuromuscular Block in the Post-Anesthetic Unit and Postoperative Complications

ConditionsPostoperative Neuromuscular BlockPostoperative Complications
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorDr. Negrin University Hospital

About this trial

The use of neuromuscular blockers (NMB) is essential to optimize surgical conditions, ensure patient immobility during the intervention and prevent complications derived from involuntary movements. Intraoperative monitoring of neuromuscular relaxation allows the depth of neuromuscular blockade to be accurately evaluated, guaranteeing ideal conditions for the surgical team. Residual neuromuscular blockade (RNMB) is the persistence of muscle paralysis after the administration of NMB during a surgical intervention. The appearance of RNMB poses substantial challenges in the postoperative period, as it has negative repercussions for the safety and well-being of the patient.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patient undergoing surgical intervention under general anesthesia that requires the use of neuromuscular block during the study time and that required hospital admission.

Informed consent signature.

Disqualifiers

Neuromuscular disease

Not having received neuromuscular block during the intervention

Admission to the outpatient surgery unit

Admission to the postoperative intensive care unit

Trial population

Patients undergoing surgical intervention under general anesthesia that requires the use of neuromuscular block during the study time.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Train-of-four

    Diagnostic test

    Patients submitted to general anesthesia with neuromuscular block will be monitored at their arrival to the Post-Anesthesia Care Unit to assess the presence of residual neuromuscular block.

Treatment groups

296 Participants
are divided into 1 treatment group
Group A: Patients submitted to General Anesthesia with Neuromuscular Block1 intervention

Trial outcomes

Primary outcomes

1

Residual Neuromuscular Block

Train-Of-Four ratio at arrival to the Post-Anesthetic Care Unit

Time frame
5 minutes postoperatively
2

Residual Neuromuscular Block

Train-Of-Four ratio 3 minutes after the arrival to the Post-Anesthetic Care Unit

Time frame
8 minutes postoperatively

Secondary outcomes

1

Postoperative complications

Postoperative complications during hospital admission

Time frame
30 days postoperatively

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Dr. Negrin University Hospital

Lead sponsor

Source ClinicalTrials.gov
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