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Resonance Breathing Training for Long Covid-related Myocardial Injury

ConditionsLong COVIDMyocardial Injury
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorChengdu Sport University

About this trial

An investigation of the efficacy of resonance breathing training in the rehabilitation of patients with Long covid-related myocardial injury

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age between 18 and 60 years;

According to the WHO definition: one or more systemic involvement present 3 months after the diagnosis of a new crown infection, and at least 2 of these months cannot be explained by other diseases

2D-STE suggestive of GLSAVG: -17% ≤ men ≤ -10%, -18% ≤ women ≤ -10%;

Consent for enrollment based on the degree of myocardial injury, as diagnosed by a clinician;

Disqualifiers

(1) Previous history of coronary atherosclerotic heart disease and heart failure; (2) Combination of severe arrhythmia or cardiogenic shock; (3) Combination of severe hypertension, hypertrophic cardiomyopathy, valvular disease of moderate or higher grade, acute myocarditis or pericarditis; (4) Combination of any disease that severely affects limb movement, such as musculoskeletal system disease or severe hepatic or renal insufficiency; (5) Combination of progressive malignant tumors, infectious diseases, bleeding disorders, autoimmune diseases, etc; Those who have serious mental illness and are unable to cooperate

Trial design

Design model

Single group

Treatments tested in this trial

  • Resonance breathing

    Other intervention

    Resonant breathing was used on the subjects, using nasal inhalation and oral exhalation, for a total of 12 weeks.

Treatment groups

70 Participants
are divided into 1 treatment group
Group A: intervention groupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

New YorkHeart Association (NYHA)

The scale is divided into four levels Grade 1 is unrestricted activity. Daily physical activity does not cause significant shortness of breath, fatigue or palpitations Grade 2 is a mild limitation of activity. Asymptomatic at rest, daily activities may cause significant shortness of breath, fatigue or palpitations Grade 3 is marked limitation of activity. May be asymptomatic at rest, but may cause significant shortness of breath, fatigue, or palpitations with less than daily activity. Grade 4 is symptomatic at rest, with discomfort associated with any physical activity. Class IVa for those who can move around indoors or at the bedside without intravenous drug administration; Class IVb for those who cannot get out of bed and require intravenous drug administration.

Time frame
12weeks
2

left ventricle global longitudinal strain, LVGLS

The magnitude of overall longitudinal myocardial strain in the left ventricle on two-dimensional speckle tracking echocardiograms as an average of the peak longitudinal strain in all myocardial segments. The normal range is (-25% to -17%) in men and (-25% to -18%) in women.

Time frame
12weeks

Secondary outcomes

1

hypertension

Blood pressure included both systolic and diastolic blood pressure and was observed before and after the intervention for any reduction in blood pressure.

Time frame
12weeks
2

Average heart rate

One-minute average heart rate (at rest).

Time frame
12weeks

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Chengdu Sport University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: