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Respiratory Outbreak Mitigation in Long-Term Care Using Point-of-Care Testing

ConditionOutbreaks
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorMichael Garron Hospital

About this trial

Outbreaks of seasonal respiratory viruses can spread rapidly in long-term care homes. Timely results for diagnostic tests remains a challenge for respiratory viruses due to the logistics of using a reference laboratory with delays leading to missed opportunities to implement virus-specific control measures to interrupt transmission resulting in larger outbreaks. Use of a point-of-care testing platform is a potential solution that provides faster results, but it is uncertain whether this translates into benefits for long-term care residents. This trial aims to assess whether rapid test results for respiratory pathogens (Influenza, Coronavirus disease of 2019 (COVID-19) and Respiratory Syncytial Virus) can impact the number and size of respiratory virus outbreaks in long-term care homes.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

No signed statement of agreement for study participation

Pre-existing use of a point-of-care testing platform

Trial design

Design model

Parallel

Treatments tested in this trial

  • Point-of-care respiratory test platform

    Device

    A point-of-care respiratory multiplex testing platform situated within a long-term care facility to provide rapid test results

  • Existing respiratory virus testing platform

    Other intervention

    Currently used respiratory virus testing platforms

Treatment groups

24 Participants
are divided into 2 treatment groups
Group A: Point-of-Care Polymerase Chain Reaction Testing PlatformExperimental treatment 1 intervention
Group B: Existing Testing Platform for Respiratory VirusesActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Number of long-term care residents infected with COVID-19, Influenza, or respiratory syncytial virus (RSV)

The number of long-term care residents who contract Influenza, COVID-19 or RSV separated into the number of residents infected after an introduction is identified and the size of an outbreak of each virus.

Time frame
7 months

Secondary outcomes

1

The number of outbreaks of Influenza, COVID-19 or RSV

The number of Influenza, COVID-19 or RSV outbreaks as declared by the local Public Health Unit

Time frame
7 months
2

The number of long-term care residents infected during an outbreak of Influenza, COVID-19 or RSV

The number of long-term care residents with a confirmed or suspected Influenza, COVID-19 or RSV infection during each outbreak as tracked by the local Public Health Unit

Time frame
28 days
3

Frequency of hospital transfers for long-term care residents infected with Influenza, COVID-19 or RSV

The number of hospital transfers for long-term care residents with Influenza, COVID-19 or RSV

Time frame
14 days
4

Number of deaths in long-term care residents infected with Influenza, COVID-19 or RSV

The number of long-term care residents who die following an infection with Influenza, COVID-19 or RSV

Time frame
28 days

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Michael Garron Hospital

Lead sponsor

Sunnybrook Health Sciences Centre

Collaborator

Humber River Health

Collaborator

Source ClinicalTrials.gov
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