Respiratory Variation of Carotid Doppler Peak Velocity (CDPV) for Non-invasive Prediction of Fluid Responsiveness

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorJohannes Gutenberg University Mainz

About this trial

The purpose of this study is to assess respiratory variation of carotid doppler peak velocity (∆CDPV) for prediction of fluid responsiveness during major abdominal surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age 18-80 years

written informed consent

scheduled major abdominal surgery

Disqualifiers

Age <18 or >80 years

pregnancy

SIRS or sepsis

any kind of cardiac arrhythmia

Trial population

Only patients scheduled for major abdominal surgery with an expected high intraoperative fluid turnover will be eligble for the study. Patients with any kind of crdiac arrhythmia, valve diseases, heart failure or carotid stenosis will be excluded from the study to avoid measurement errors and bias for the hemodynamic parameters such as pulse pressure variation, stroke volume and carotid doppler peak velocity.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Change in stroke volume following a fluid bolus.

A rise in stroke volume of ≥10% following a fluid bolus of 7ml/kg Ideal Body Weight is considered to reflect fluid responsiveness. Measurements will be assessed through esophageal doppler monitoring.

Time frame
Immediately before and 1 minute after completion of each fluid bolus.

Secondary outcomes

Other outcomes

Sponsors and contacts

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