About this trial
The purpose of this study is to assess respiratory variation of carotid doppler peak velocity (∆CDPV) for prediction of fluid responsiveness during major abdominal surgery.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age 18-80 years
written informed consent
scheduled major abdominal surgery
Disqualifiers
Age <18 or >80 years
pregnancy
SIRS or sepsis
any kind of cardiac arrhythmia
Trial population
Only patients scheduled for major abdominal surgery with an expected high intraoperative fluid turnover will be eligble for the study. Patients with any kind of crdiac arrhythmia, valve diseases, heart failure or carotid stenosis will be excluded from the study to avoid measurement errors and bias for the hemodynamic parameters such as pulse pressure variation, stroke volume and carotid doppler peak velocity.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Change in stroke volume following a fluid bolus.
A rise in stroke volume of ≥10% following a fluid bolus of 7ml/kg Ideal Body Weight is considered to reflect fluid responsiveness. Measurements will be assessed through esophageal doppler monitoring.
Sponsors and contacts
Click on the lead sponsor to view all of their trials.