About this trial
This multicenter prospective observational non-pharmacological study aims to evaluate resting energy expenditure (REE) in pediatric patients affected by inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. REE will be measured using indirect calorimetry and estimated using predictive equations. The study also aims to investigate the relationship between REE, disease activity, and dietary or pharmacological treatments. Clinical, laboratory, anthropometric, nutritional, and disease activity data will be collected during routine clinical follow-up at diagnosis, after induction therapy, and during follow-up visits.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Pediatric patients aged 6 to 17 years
New diagnosis of inflammatory bowel disease, including Crohn disease or ulcerative colitis, according to ECCO/ESPGHAN criteria
Written informed consent signed by parents or legal guardians
Disqualifiers
Intestinal surgery within 6 weeks before the first evaluation
Parenteral or enteral nutrition within 6 weeks before the first evaluation
Eating disorders or other chronic diseases associated with possible malabsorption
Trial population
Pediatric patients aged 6 to 17 years with newly diagnosed inflammatory bowel disease, including Crohn disease and ulcerative colitis, recruited from participating Italian centers with availability of indirect calorimetry assessment.
Trial design
Cohort
Prospective
Treatments tested in this trial
Indirect Calorimetry
Diagnostic testResting energy expenditure (REE) assessment performed using indirect calorimetry in pediatric patients with inflammatory bowel disease during routine clinical follow-up. Measurements are obtained under resting conditions after fasting and are used to evaluate energy metabolism and its relationship with disease activity and treatments.
Treatment groups
Trial outcomes
Primary outcomes
Resting Energy Expenditure measured by indirect calorimetry
Assessment of resting energy expenditure (REE) in pediatric patients with inflammatory bowel disease using indirect calorimetry and comparison with predictive equations.
Sponsors and contacts
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