RESTORE-BLADDER (REgistry on STrategies for Organ pREservation in Muscle-invasive BLADDER Cancer)

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHeinrich-Heine University, Duesseldorf

About this trial

Removal of the urinary bladder (radical cystectomy) is a major surgical procedure that can have a permanent impact on a patient's quality of life. Consequently, some patients, despite having received comprehensive counseling and completing systemic therapy, decide against subsequent surgery or alternative radiotherapy. Recent scientific studies suggest that, for selected patients, an attempt at bladder preservation may be a medically justifiable option. However, it remains unclear which patients are truly suitable candidates for bladder-preserving management and which are not. The aim of this registry is therefore to collect and analyze clinical data from this specific patient population.

Eligibility criteria

Qualifiers

Patients aged >= 18 years, capable of providing informed consent

Histologically confirmed muscle-invasive urothelial carcinoma of the urinary bladder

Received perioperative systemic therapy in accordance with current guidelines and subsequently decline cystectomy or radiotherapy

Disqualifiers

Age < 18 years

Lack of capacity to provide informed consent

No histological confirmed muscle-invasive urothelial carcinoma

No prior preoperative systemic therapy

Trial design

Treatments tested in this trial

  • None. Registry.

Treatment groups

No treatment groups listed

Locations

This trial has no locations