Retinal Imaging in Patients With Inherited Retinal Degenerations
ConditionRetinitis Pigmentosa
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age13+
SponsorUniversity of California, San Francisco
About this trial
The purpose of this study is to determine whether the structure and function of the human retina can be studied with high resolution in patients with inherited retinal degenerations using the Adaptive Optics Scanning Laser Ophthalmoscope (AOSLO).
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Subjects must speak and understand English
Subjects must have pupils that dilate to at least 6 millimeters diameter.
Subjects must be willing to travel to University of California (UC) Berkeley.
Subjects are financially responsible for their travel to the San Francisco area if they are not San Francisco residents.
Disqualifiers
Cataract
Irregular corneal astigmatism (keratoconus)
Prior refractive surgery
Trial population
Patients with inherited retinal degenerations, including retinitis pigmentosa, choroideremia, x-linked retinoschisis and Usher syndrome. We are also studying a small number of patients with age-related macular degeneration.
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Cone spacing
The current study will assess cone spacing twice at baseline and every 6 months for 30 months. The primary outcome will be measured at 24 months.
Time frame
24 monthsSecondary outcomes
1
Visual acuity
Visual acuity will be measured every 6 months for 30 months with the primary outcome measure at 24 months.
Time frame
24 monthsSponsors and contacts
Click on the lead sponsor to view all of their trials.
University of California, San Francisco
Lead sponsor
University of California, Berkeley
Collaborator
Source ClinicalTrials.gov