Retrolaminar Plane Block Versus Anterior Quadratus Lumborum Block in Pediatric Urogenital Surgery
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-12
SponsorIstanbul University - Cerrahpasa
About this trial
Effective control of postoperative pain following pediatric lower urogenital surgery is important for enhancing recovery and reducing opioid requirements. Anterior quadratus lumborum block and retrolaminar block are two ultrasound-guided truncal block techniques used for perioperative analgesia in lower abdominal surgery. However, direct comparisons of their analgesic efficacy in pediatric lower urogenital procedures remain limited.
This prospective, randomized, controlled trial will enroll 76 pediatric patients aged 6 months to 12 years with American Society of Anesthesiologists physical status I-III who are scheduled for elective lower urogenital surgery. Participants will be randomly assigned in a 1:1 ratio to receive either an anterior quadratus lumborum block or a retrolaminar block. Both techniques will be performed under ultrasound guidance in addition to standardized general anesthesia.
The primary outcome will be rescue analgesic requirement during the first 24 postoperative hours. Secondary outcomes will include postoperative pain scores, time to first rescue analgesic administration, intraoperative remifentanil consumption, adverse effects such as nausea and vomiting, and caregiver satisfaction. The study aims to compare the postoperative analgesic efficacy and safety of anterior quadratus lumborum block and retrolaminar block in pediatric patients undergoing lower urogenital surgery.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age between 6 months and 12 years
Scheduled for lower abdominal urogenital surgery (e.g., inguinal hernia repair or orchiopexy for undescended testis)
American Society of Anesthesiologists physical status classification I-III
Written informed consent obtained from a parent or legal guardian
Disqualifiers
History of allergy to local anesthetic agents
Presence of infection at the planned injection site
Coagulopathy or any other condition contraindicating regional anesthesia
Planned laparoscopic orchiopexy
Trial design
Design model
Parallel
Treatments tested in this trial
Anterior Quadratus Lumborum Block
Procedure/SurgeryAn ultrasound-guided anterior quadratus lumborum block will be performed after induction of general anesthesia. Following identification of the quadratus lumborum and psoas major muscles, 0.25 percent bupivacaine will be injected into the fascial plane between these muscles at a volume of 0.4 milliliters per kilogram.
Retrolaminar Block
Procedure/SurgeryAn ultrasound-guided retrolaminar block will be performed after induction of general anesthesia. After identification of the target vertebral lamina, 0.25 percent bupivacaine will be administered into the retrolaminar plane at a volume of 0.4 milliliters per kilogram.
Treatment groups
76 Participants
are divided into 2 treatment groupsGroup A: Anterior Quadratus Lumborum Block GroupExperimental treatment 1 intervention
Group B: Retrolaminar Block GroupExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Total Rescue Analgesic Requirement During the First 24 Postoperative Hours
Total rescue analgesic consumption during the first 24 postoperative hours will be recorded. Pain assessment will be performed using the Face, Legs, Activity, Cry, and Consolability Scale. The scale ranges from 0 to 10, with higher scores indicating greater pain intensity. Rescue analgesia will be administered when the score is 4 or higher.
Time frame
First 24 hours after surgerySecondary outcomes
1
Postoperative Pain Scores
Pain intensity will be assessed using the Face, Legs, Activity, Cry, and Consolability Scale. Scores range from 0 to 10, with higher scores indicating greater pain intensity.
Time frame
Postoperative 1, 2, 4, 8, 16, and 24 hours2
Time to First Rescue Analgesic Administration
The time from completion of surgery to the administration of the first rescue analgesic will be recorded in minutes.
Time frame
First 24 hours after surgery3
Intraoperative Remifentanil Consumption
Total remifentanil consumption during surgery will be recorded in micrograms per kilogram.
Time frame
From induction of anesthesia until the end of surgerySponsors and contacts
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Source ClinicalTrials.gov
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