The primary aim of this study is to evaluate changes in absolute coronary flow and pressure before and after percutaneous coronary intervention in calcified lesions. The secondary aim is to use a machine learning model to predict the outcome of the intervention.
Age > 18 years
Moderate (40-90 %) epicardial disease
Vessel suitable for PCI and intracoronary imaging
De novo-lesions
eGFR < 40ml/min
ACS < 48 hours
Patient without ability to provide informed consent
Patient with left main stenosis
This a prospective clinical cohort study recruiting patients with stable coronary artery disease referred to invasive coronary angiography on clinical indication with angiographic calcium and eligible for PCI.
Cohort
Prospective
Measurement of coronary flow and pressure
Diagnostic testThe pressure and flow data will be integrated in a machine learning model
Post-PCI FFR
FFR is measured after PCI is completed.
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