To explore the 5-year overall survival (OS) of right versus left thoracic surgical approaches for patients with locally advanced Siewert II gastroesophageal junction adenocarcinoma treated by neoadjuvant chemotherapy
Histologically confirmed gastroesophageal adenocarcinoma;
R0 resectable Siewert Ⅱ, cT2-3N0-3M0 (AJCC V8 TNM classification);
Have a performance status of 0 or 1 on the ECOG Performance Scale;
Age 18-80 years old, both men and women;
Have a history of other malignant tumors in the past or at the same time;
Previous upper abdominal surgery (excluding cholecystectomy);
Bleeding, perforation and obstruction requiring emergency surgical treatment;
Severe heart, lung, liver and kidney dysfunction, which the researcher thinks is not suitable for operation;
Parallel
different thoracic surgical approaches
Procedure/SurgeryRight Versus Left Thoracic Surgical Approaches
OS rate
OS is defined as the time from randomization to death due to any cause.
DFS rate
DFS is defined as the time from randomization to the first documented disease progression of local recurrence or distant metastasis or death due to any cause.
pCR rate
PCR is defined as pT0N0M0
MPR rate
MPR is defined as viable tumor comprised ≤ 10% of resected tumor specimens.
Operative Complications
Operative Complications
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