Ripening Approaches for Prompt Induction and Delivery - Sequential Versus Concurrent Dilapan-S and Misoprostol to Achieve Vaginal Delivery (RAPID-DS)

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorOchsner Health System

About this trial

The purpose of this study is to compare the effectiveness of sequential versus combined multimodal cervical ripening strategies to achieve vaginal delivery within 24 hours among nulliparous patients with singleton, vertex pregnancies at term undergoing induction of labor.

Eligibility criteria

Qualifiers

Nulliparous patients with singleton pregnancies with vertex lie at term receiving prenatal care that are eligible for outpatient cervical ripening will be eligible

Disqualifiers

age less than 18,

suspected major fetal anomalies (including suspected or proven chromosome anomalies, congenital cardiac disease expected to require neonatal intervention, and multiple anomalies suggestive of a complex syndrome),

fetal growth restriction

oligohydramnios

Trial design

Treatments tested in this trial

  • Sequential Cervical Ripening
  • Inpatient Combined Cervical Ripening

Treatment groups

260 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Ochsner Health System

Lead sponsor

Medicem International

Collaborator