Health TrialsbyHealthPanel

Risk Factors and Outcomes of Hepatitis A in Children

ConditionsHepatitis AAcute Hepatitis
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age1-18
SponsorAssiut University

About this trial

This prospective observational study aims to evaluate the risk factors, clinical course, and outcomes among children with acute hepatitis A infection admitted to Assiut University Children Hospital.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age 1 month to 18 years

Confirmed acute hepatitis A infection by positive Anti-HAV IgM

Written informed consent from parents or legal guardians

Disqualifiers

- Co-infection with hepatitis B, hepatitis C, or hepatitis E

Chronic liver diseases (autoimmune hepatitis, Wilson disease, metabolic liver diseases)

Trial population

Children with confirmed acute hepatitis A infection admitted to or presenting at Assiut University Children Hospital.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

190 Participants
are grouped into 1 trial group
Group A: Single cohort: Children with acute hepatitis A

Trial outcomes

Primary outcomes

1

Proportion of children with unfavorable outcome

Proportion of children who develop one or more of the following during hospital stay: acute liver failure, hepatic encephalopathy, acute kidney injury, ICU admission, prolonged hospital stay (\>7 days), or death.

Time frame
Baseline

Secondary outcomes

1

Proportion of children with acute liver failure

Proportion of children who develop acute liver failure during hospital stay.

Time frame
Baseline
2

Proportion of children with hepatic encephalopathy

Proportion of children who develop hepatic encephalopathy (any West Haven grade) during hospital stay.

Time frame
Baseline
3

Mean duration of hospital stay

Mean number of days of hospitalization.

Time frame
Baseline
4

Proportion of children requiring ICU admission

Proportion of children who require intensive care unit admission.

Time frame
Baseline

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assiut University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: