Risk Factors of Failure of Conservative Treatment in Acute Non Complicated Appendicitis

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age16-60
SponsorAhmed Mohammed Hussein Sayed

About this trial

From this study, it can be concluded that patients who meet the following criteria are more likely to fail expectant management and thus should not be considered for the NOM of uncomplicated acute appendicitis. These include the duration of symptoms before presenting to a surgical emergency , the presence of fever within 24 hours of presenting to a surgical emergency, TLC cells/dL, CRP mg/L, appendix diameter mm, modified Alvarado score , and adult appendicitis score .

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Male or female patients é diagnosis of acute appendicitis .

Patients with ages: from 16 to 60 years old.

Disqualifiers

complicated AA (appendicolith, perforation, peri appendicular abscess or suspicion of a tumor).

inflammatory bowel disease.

inability to co-operate and give informed consent.

diffuse peritonitis.

Trial population

Male or female patients é diagnosis of acute appendicitis Patients with ages: from 16 to 60 years old

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • ceftriaxone

    Drug

    ceftriaxone 1 gm/12 hourly and IV metronidazole 500 mg/8 hourly

  • ceftriaxone 1 gm/12 hourly and IV metronidazole 500 mg/8 hourly

    Drug

    Conservative management

Treatment groups

100 Participants
are divided into 1 treatment group
Group A: (1) Male or female patients é diagnosis of acute appendicitis.2 interventions

Trial outcomes

Primary outcomes

1

Risk factors of failure of conservative treatment in acute non complicated appendicitis

modified Alvarado score and adult appendicitis score

Time frame
One year

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Ahmed Mohammed Hussein Sayed

Lead sponsor

Assiut University

Sponsor institution

Assiut University

Collaborator

This trial is not recruiting at the moment. You can still explore other options: