About this trial
REDEEM-CAD is a prospective multi-centre study of CAD risk evaluation and management in cancer survivors 40-70 years with chemotherapy or radiotherapy \>5 years ago.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
Unable to provide written informed consent to participate in this study
Known coronary artery disease at recruitment
History of previous coronary artery disease
Inability to acquire interpretable CT images
Trial population
Cancer survivors 40-70 years with chemotherapy or radiotherapy \>5 years ago
Trial design
Cohort
Prospective
Treatments tested in this trial
Coronary CT
Diagnostic testScreening/Management Plan
Treatment groups
Trial outcomes
Primary outcomes
Proportion of evaluated patients who should undergo CAD prevention
High clinical risk, or intermediate risk with CAC score \>0
Secondary outcomes
Proportion with critical CAD
Coronary stenosis \>70% by CT coronary angiogram
Proportion at intermediate clinical risk
Intermediate clinical risk (0.8-2.0% annualized risk by Pooled Cohort Equation)
Statin responsiveness
Change in plaque volume
Sponsors and contacts
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Baker Heart and Diabetes Institute
Lead sponsor
Western Health, Australia
Collaborator
Northern Hospital, Australia
Collaborator
Menzies Institute for Medical Research
Collaborator
Peter MacCallum Cancer Centre, Australia
Collaborator
The Alfred
Collaborator