Risk-guided Disease managEment Plan to prevEnt CAD in Patients Treated With Previous Cancer

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40-70
SponsorBaker Heart and Diabetes Institute

About this trial

REDEEM-CAD is a prospective multi-centre study of CAD risk evaluation and management in cancer survivors 40-70 years with chemotherapy or radiotherapy \>5 years ago.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

Unable to provide written informed consent to participate in this study

Known coronary artery disease at recruitment

History of previous coronary artery disease

Inability to acquire interpretable CT images

Trial population

Cancer survivors 40-70 years with chemotherapy or radiotherapy \>5 years ago

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Coronary CT

    Diagnostic test

    Screening/Management Plan

Treatment groups

748 Participants
are divided into 2 treatment groups
Group A: Survivor Screening/Management Plan1 intervention
Group B: Non-cancer Screening/Management Plan1 intervention

Trial outcomes

Primary outcomes

1

Proportion of evaluated patients who should undergo CAD prevention

High clinical risk, or intermediate risk with CAC score \>0

Time frame
3 years

Secondary outcomes

1

Proportion with critical CAD

Coronary stenosis \>70% by CT coronary angiogram

Time frame
3 years
2

Proportion at intermediate clinical risk

Intermediate clinical risk (0.8-2.0% annualized risk by Pooled Cohort Equation)

Time frame
3 years
3

Statin responsiveness

Change in plaque volume

Time frame
3 year follow-up

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Baker Heart and Diabetes Institute

Lead sponsor

Western Health, Australia

Collaborator

Northern Hospital, Australia

Collaborator

Menzies Institute for Medical Research

Collaborator

Peter MacCallum Cancer Centre, Australia

Collaborator

The Alfred

Collaborator