About this trial
The main objectives of PPS3-2 are (i) to describe the dynamics of vascular aging and baroreflex sensitivity 12 to 16 years a part, (ii) to identify their determinants, and (iii) to quantify the subsequent risk of cardiovascular diseases.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Being enrolled in PPS3 and having signed an informed consent for PPS3-2
Disqualifiers
Institutionalized participants
Participants under guardianship
Participants under judicial safeguard measure
Trial population
Men and women aged 60 to 95 years who are participants of the PPS3 study and have accepted to undergo a second physical examination and answer to health questionnaires in primary care health centre in Paris that is subsidized by the French Health Insurance System.
Trial design
Cohort
Prospective
Treatments tested in this trial
high-precision carotid echo-tracking
Other interventionevaluation of vascular aging parameters and baroreflex sensitivity
Treatment groups
Trial outcomes
Primary outcomes
carotid diameter
high precision carotid echo tracking diameter in mm
intima media thickness
high precision echo tracking intima media thickness of the common carotid artery in mm
carotid plaques
high precision carotid echo tracking carotid plaques
wall cross sectional area
high precision carotid echo tracking carotid wall cross sectional area, mm2
Secondary outcomes
brachial artery diameter
ultra high frequency ultrasound radial artery diameter in mm
thickness of the intima media of the radial artery
ultra high frequency ultrasound radial artery intima media thickness in mm
arterial plaques
ultra high frequency ultrasound radial artery plaques
wall cross sectional area of the radial artery
ultra high frequency ultrasound radial artery wall cross sectional area, mm2
Sponsors and contacts
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