About this trial
To evaluate the autologous platelet rich plasma and platelet rich fibrin glue effect on the treatment of anal fistula
To asses role of platelet rich plasma and platelet rich fibrin glue in decreasing recurrence of perianal fistula
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
60 patients with perianal fistula were in the age group between 20 to 60 years old
Disqualifiers
Thrombocytopenia
Patient with rectovaginal fistula
fistula with chronic cavities
Acute sepsis and patient were not willing undergo this type of treatment
Trial design
Single group
Treatments tested in this trial
PRP and PRFG in treatment of anal fistula
Other interventionThe tract fistula was cleaned with betadine 10% before PRP and PRFP were applied. Then, 2 ml of PRP was injected around the fistula into the tissue (the penetration depth in injection was 5-6 mm), and 4 ml PRFP was mixed with 1 m thrombin and interpositioned into the tract. 2 ml of PRP was injected around the fistula into the tissue (the penetration depth in injection was 5-6 mm), and 4 ml PRFP was mixed with 1 m thrombin and interpositioned into the tract. The operation time was about 20-30 minutes, the clot formation usually takes about 8 minutes, but the anesthesia was extended to 20 minutes to make sure a complete clot in the place of fistula
Treatment groups
Trial outcomes
Primary outcomes
evaluate effect of autologous platelet rich plasma and platelet rich fibrin glue in decreasing recurrence rate of anal fistula
evaluate effect of autologous platelet rich plasma and platelet rich fibrin glue in decreasing recurrence rate of anal fistula
Secondary outcomes
to evaluate the role of platelet rich plasma and platelet rich fibrin glue in decreasing post operative complication of anal fistula
to evaluate the role of platelet rich plasma and platelet rich fibrin glue in decreasing post operative complication of anal fistula
Locations
Sponsors and contacts
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