Role of Autologous Platelet Rich Plasma(PRP) Injection and Platelet Rich Fibrin Glue(PRFG) Interposition for Treatment of Anal Fistula

ConditionAnal Fistula
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-60
SponsorAssiut University

About this trial

To evaluate the autologous platelet rich plasma and platelet rich fibrin glue effect on the treatment of anal fistula

To asses role of platelet rich plasma and platelet rich fibrin glue in decreasing recurrence of perianal fistula

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

60 patients with perianal fistula were in the age group between 20 to 60 years old

Disqualifiers

Thrombocytopenia

Patient with rectovaginal fistula

fistula with chronic cavities

Acute sepsis and patient were not willing undergo this type of treatment

Trial design

Design model

Single group

Treatments tested in this trial

  • PRP and PRFG in treatment of anal fistula

    Other intervention

    The tract fistula was cleaned with betadine 10% before PRP and PRFP were applied. Then, 2 ml of PRP was injected around the fistula into the tissue (the penetration depth in injection was 5-6 mm), and 4 ml PRFP was mixed with 1 m thrombin and interpositioned into the tract. 2 ml of PRP was injected around the fistula into the tissue (the penetration depth in injection was 5-6 mm), and 4 ml PRFP was mixed with 1 m thrombin and interpositioned into the tract. The operation time was about 20-30 minutes, the clot formation usually takes about 8 minutes, but the anesthesia was extended to 20 minutes to make sure a complete clot in the place of fistula

Treatment groups

60 Participants
are divided into 1 treatment group
Group A: PRP and PRFG in anal fistulaExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

evaluate effect of autologous platelet rich plasma and platelet rich fibrin glue in decreasing recurrence rate of anal fistula

evaluate effect of autologous platelet rich plasma and platelet rich fibrin glue in decreasing recurrence rate of anal fistula

Time frame
3 year

Secondary outcomes

1

to evaluate the role of platelet rich plasma and platelet rich fibrin glue in decreasing post operative complication of anal fistula

to evaluate the role of platelet rich plasma and platelet rich fibrin glue in decreasing post operative complication of anal fistula

Time frame
3 year

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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