Role of Oral Care in Prevention of Nosocomial Pneumonia Among COPD Patients
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssiut University
About this trial
Poor dental hygiene has been linked to respiratory pathogen colonization in ICU patients. Therefore, respiratory pathogens tend to colonize dental plaque and oral mucosa in these populations. Therefore, strategies to eliminate respiratory pathogens from the oral cavity may improve oral hygiene and decrease the development of nosocomial pneumonia.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients diagnosed as COPD
admitted to ICU with acute exacerbation
need for noninvasive ventilatory support including noninvasive ventilation anf high flow nasal cannula
Disqualifiers
patients refusing to participate
End stage organ failure (Heart Failure, Liver cell failure and/or Renal failure
Trial design
Design model
Parallel
Treatments tested in this trial
Oral care
Other interventionOral care done twice daily with chlorhexidine oral care solution (concentration 1.2%)
Treatment groups
60 Participants
are divided into 2 treatment groupsGroup A: Routine oral care (Group 1)Placebo comparator 1 intervention
Group B: Chlorhexidine oral careActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Incidence of nosocomial pneumonia
Incidence of nosocomial pneumonia diagnosed via clinical features and confirmed with either chest ultrasonography or chest radiography
Time frame
1 monthSponsors and contacts
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Source ClinicalTrials.gov