About this trial
Despite its low spatial resolution, peripheral vision is very useful for rapidly categorizing a visual scene. Low spatial frequencies of a visual stimulus available in peripheral vision would allow a coarse categorization of the scene and objects (deciding, for example, whether it is an urban or natural landscape). This first representation would then trigger predictive mechanisms which would subsequently guide a more detailed visual analysis in central vision. The psychophysical studies that the investigators have already conducted in this scientific context has been carried out under normal vision conditions. The objective of this project is to study the influence of peripheral vision on central vision with an original approach: What are the consequences of a loss of peripheral vision on the processing performed in central vision? The project will concern patients with glaucoma. This ophthalmic pathology particularly affects the peripheral retina and thus represents a good pathological cognitive model of a visual recognition system in which peripheral vision is less important. The investigators will conduct psychophysical studies with glaucomatous patients and healthy volunteers with normal vision. All participants will be required to perform a short experiment on a computer (15 minutes) where they will look at different photographs of scenes of different luminance and spatial frequencies. Participants will have to perform various tasks on these images using the keys on the keyboard.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
between 18 and 80 years old
stable bilateral primary open angle glaucoma (POAG)
visual acuity > 5/10 for distant vision for the eye tested
peripheral visual field defect on the eye tested measured through a Humphrey Visual Field Analyzer
Disqualifiers
ophthalmologic disease other than Glaucoma (age-related macular degeneration, cataract except for uncomplicated cataract surgery, amblyopia, optic neuropathy, diabetic retinopathy …)
treated with medication that might compromise sustained attention (benzodiazepine, narcoleptics)
Trial population
POAG patients and age-matched normally sighted controls
Trial design
Case-control
Prospective
Treatments tested in this trial
Psychophysical evaluation
BehavioralAll participants will be required to perform a short experiment on a computer (15 minutes) where they will look at different photographs of scenes of different luminance and spatial frequencies. They will have to perform various tasks on these images using the keys on the keyboard.
Treatment groups
Trial outcomes
Primary outcomes
Psychophysical measure : Percentage of correct response
Measure calculated by the comparison between the expected response and the response provided by the participant for each trial of the experiment
Psychophysical measure : Mean reaction time in milliseconds
Measure calculated by averaging the time in milliseconds taken by the participant to provide the response for each trial of the experiment
Locations
Sponsors and contacts
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