Health TrialsbyHealthPanel

Rural Water Filtration and Health Study

ConditionsDiarrheaEnteric PathogensGastrointestinal DiseaseWaterborne Diseases
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6+
SponsorVirginia Polytechnic Institute and State University

About this trial

The goal of this intervention trial is to learn if the use of drinking water filters will result in improved health outcomes for people living in homes with well water and spring water in rural regions of Central Appalachia.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Home is located in a study county in southwest Virginia or northeast Tennessee

There is at least one adult (aged 18 or older) who regularly (>6 months per year) resides in the household

Household does not have utility-supplied water (and <33% of household members regularly drink bottled water)

Reported household income is <80% of the county median income (based on US Department of Housing and Urban Development thresholds by household population)

Disqualifiers

None (no exclusion criterion based on gender, race, ethnicity, language, or literacy)

Trial design

Design model

Parallel

Treatments tested in this trial

  • Water filter

    Device

    Point-of-use multi-stage dispenser water filter with a membrane microfilter and a combined activated carbon and ion exchange filter

Treatment groups

1,584 Participants
are divided into 2 treatment groups
Group A: Point-of-use water filterExperimental treatment 1 intervention
Group B: ControlNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Acute gastrointestinal illness incidence

Incidence of household-level acute gastrointestinal illness (AGI), based on individual-level reported 7-day AGI. AGI case definition: reported diarrhea today and/or any day in the last seven days. Individual-level reported fever, nausea, cramps, and vomiting data will also be collected. For those with reported AGI, investigators will also ask if they had three or more loose stools in a 24-hour period.

Time frame
12 months

Secondary outcomes

1

Waterborne pathogen infections

Detection of one or more pathogens that are either exclusively waterborne or highly likely to be waterborne via analysis of saliva and stool samples for bacterial, protozoal, and viral targets.

Time frame
12 months
2

E. coli or pathogens in water samples

Detection of E. coli in collected well and spring water samples or detection of enteric pathogens in filtered well and spring water samples.

Time frame
12 months

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Virginia Polytechnic Institute and State University

Lead sponsor

East Tennessee State University

Collaborator

University of North Carolina, Chapel Hill

Collaborator

University of California, Berkeley

Collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: