Rutgers University Study of the Genetics of Pulmonary Hypertension

ConditionsPulmonary Hypertension Pulmonary Arterial Hypertension Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)Pulmonary Arterial Hypertension Associated With Connective Tissue Disease Pulmonary Arterial Hypertension Associated With Connective Tissue Disease (Disorder)Pulmonary Arterial Hypertension Associated With Schistosomiasis (Disorder)Pulmonary Arterial Hypertension of Congenital Heart Disease Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorRutgers, The State University of New Jersey

About this trial

The goal of this observational study is to learn more about how genes impact the risk of pulmonary hypertension. Anyone 18 or older living in the US is eligible, and a diagnosis of PH is NOT required. Study participation is online, and it takes about 20 minutes to complete health surveys and request a saliva collection kit sent through US mail. In return, study participants may opt to receive information about their genetic ancestry at no cost.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

age 18 years or older

currently living in the United States

able to understand and follow written instructions in English

have access to the internet and a computer, laptop, tablet or smart phone

Disqualifiers

Age 17 or below

Not currently living in the United States

Not able to participate in an online research study in English

Trial population

The study population consists of anyone at least 18 years old who lives in the United States, including both individuals who have or had pulmonary hypertension and those who have not. Participants include males, females, non-binary, and all race-ethnic groups.

Trial design

Design model

Case-control

Time perspective

Cross-sectional

Treatments tested in this trial

Saliva sample
Genetic
Saliva sample is sent via prepaid US Mail for DNA extraction
Health surveys
Other intervention
Health surveys are filled out online in the study portal.

Treatment groups

10,000 Participants

are divided into 2 treatment groups

Group A: Pulmonary hypertension cases2 interventions

Group B: Pulmonary hypertension controls2 interventions

Trial outcomes

Primary outcomes

Genetic risk variants associated with pulmonary hypertension

Genetic factors will be measured through whole exome sequencing along with genotyping of common variants, and then correlated with pulmonary hypertension and pulmonary hypertension subtype.

Time frame

2 years

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Rutgers, The State University of New Jersey

Lead sponsor

Source ClinicalTrials.gov

Apply now