The purpose of this study is to explore the efficacy and safety of remote ischemic conditioning for essential hypertension in the community population.
Age≥30 years, ≤ 75 years, regardless of sex;
Patients with a history of essential hypertension and systolic blood pressure (SBP) ≥140 mmHg in three blood pressure measurements performed on separate days within 3 days prior to enrollment.
Signed and dated informed consent is obtained.
Blood pressure ≥ 180/110mmHg;
Planned adjustment of antihypertensive drugs within the next 3 weeks;
Severe hematologic disorders or significant coagulation abnormalities;
Individuals who had contraindication of remote ischemic conditioning, such as severe soft tissue injury, fracture or vascular injury in the upper limb, acute or subacute venous thrombosis, arterial occlusive disease, subclavian steal syndrome, etc;
Parallel
Patients are treated with previous antihypertensive treatment plus remote ischemic conditioning.
DeviceRemote ischemic conditioning (RIC) is induced by 4 cycles of 5 min of upper limb ischemia followed by 5 min reperfusion. Limb ischemia was induced by inflation of a blood pressure cuff to 200 mmHg.
Previous antihypertensive treatment
Other interventionPatients are only treated with previous antihypertensive treatment.
Changes of mean systolic blood pressure
The mean systolic blood pressure in the last 3 days of treatment minus baseline mean systolic blood pressure
Mean systolic blood pressure level
Mean systolic blood pressure levels during the last 3 days of treatment
Changes of mean diastolic blood pressure
The mean diastolic blood pressure in the last 3 days of treatment minus baseline mean diastolic blood pressure
Mean diastolic blood pressure level
Mean diastolic blood pressure levels during the last 3 days of treatment
Blood pressure target achievement rate
Blood pressure target achievement rate after treatment
Click on the lead sponsor to view all of their trials.
Yi Yang
Lead sponsor
The First Hospital of Jilin University
Sponsor institution
