Health TrialsbyHealthPanel

Sarcopenia and Intervention Physical Therapy

ConditionSarcopenia
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60-75
SponsorPharos University in Alexandria

About this trial

To evaluate and compare the effectiveness of neuromuscular electrical stimulation (NMES) and low-load resistance training with blood flow restriction (BFR) in improving muscle mass, strength, functional performance, and quality of life in elderly individuals diagnosed with sarcopenia

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Older age (≥ 60-75 years)

Disqualifiers

heart disese

kidny disese

autoimune disese

cognetive disorder

Trial design

Design model

Crossover

Treatments tested in this trial

  • Neuromuscular Electrical Stimulation (NMES) Group,Resistance + BFR Group

    Device

    NMES Group: Receives neuromuscular electrical stimulation to the thigh muscles for 30 minutes, three times per week, over 8 weeks. Resistance + BFR Group: Performs low-load resistance exercises with blood flow restriction applied to the thighs, also for 30 minutes per session, three times per week, over 8 weeks. Control Group: Receives placebo treatment using a turned-off stimulation device with no active intervention during the 8-week period.

Treatment groups

60 Participants
are divided into 3 treatment groups
Group A: Neuromuscular Electrical Stimulation (NMES) GroupExperimental treatment 1 intervention
Group B: Resistance + BFR GroupExperimental treatment 1 intervention
Group C: Control GroupPlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

1

Change in Muscle Mass

Assessed using Bioelectrical Impedance Analysis (BIA) to measure skeletal muscle mass. Evaluation is done pre- and post-intervention to detect changes in the Skeletal Muscle Index (SMI), based on EWGSOP2 criteria

Time frame
2 month

Secondary outcomes

1

Muscle Strength Handheld dynamometer (e.g., MicroFET)

Isometric knee extension strength Measurement: Pre- and post-intervention, using the highest or average value from 2-3 trials.

Time frame
2 month
2

Timed Up and Go (TUG) Test

Assesses eight domains of health-related quality of life, scored from 0 to 100. Administered before and after the intervention period

Time frame
2 month

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Pharos University in Alexandria

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: