Sarcopenia in Acute Ischemic Stroke

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50+
SponsorUniversity Clinical Hospital na V.V.Vinogradov (branch of RUDN university na Patrice Lumumba)

About this trial

The objective of this observational study is to determine the prevalence of sarcopenia in patients aged 50 years and older with acute ischemic stroke, to characterize its trajectory during the acute phase using instrumental verification and functional-cognitive assessments, and to evaluate its impact on functional outcome at three months. The main research question is:

Is the presence of sarcopenia at admission associated with less favorable stroke outcomes, including higher rates of complications and mortality?

Participants receiving standard medical care for acute ischemic stroke will undergo extended functional assessment for sarcopenia, and a subset will additionally undergo cognitive evaluation.

Eligibility criteria

Qualifiers

Age 50 years and older

Acute ischemic stroke confirmed by CT or MRI

Admission within the first 72 hours

Written informed consent and availability of a contact telephone number for follow-up

Disqualifiers

TIA without a visible lesion on neuroimaging; bilateral hemiparesis

Amputations or severe contractures that preclude anthropometric assessment

Active cancer at stage IV or life expectancy of less than 3 months

Neuromuscular diseases; chronic use of systemic glucocorticoids for more than 3 months

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed