Screening for Dysglycemia During Postpartum Period in Women With GDM

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
AgeNot listed
SponsorUniversity of Sao Paulo General Hospital

About this trial

Gestational diabetes mellitus (GDM) is one of the most common clinical conditions in pregnancy, with an increasing incidence due to the rise in overweight women and the postponement of motherhood. It is associated with perinatal complications and an increased risk of developing prediabetes and type 2 diabetes after delivery. Therefore, it is recommended that a 75g oral glucose tolerance test (OGTT-75g) be performed between 6 and 12 weeks postpartum. Despite its relevance, the rate of adherence to the test is low. Recent studies also indicate that measuring blood glucose one hour after the overload may be more sensitive than the traditional two-hour measurement in the early detection of dysglycemia. This study aims to evaluate strategies for qualifying the screening of metabolic changes in the postpartum period among women with GDM. The objectives are: (1) to analyze the impact of sending reminders via WhatsApp on the attendance rate for the 75g OGTT; and (2) to compare the frequency of prediabetes and diabetes diagnoses using two different diagnostic strategies applied to the same test-the traditional (fasting and 2-hour blood glucose) and the alternative (fasting and 1-hour blood glucose).

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

initial fasting blood glucose ≥ 92mg/dL OR

75g oral glucose tolerance test with fasting ≥ 92mg/dL or after 1h ≥ 180mg/dL or after 2h ≥ 153mg/dL Delivery performed at HC-FMUSP Scheduling of the 75g oral glucose tolerance test between 6 and 12 weeks after delivery Agreement with the informed consent form

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Whatsapp message

    Other intervention

    Automatic reminder messages via WhatsApp on days D-7 and D-3 in relation to the scheduled date for the exam.

Treatment groups

182 Participants
are divided into 2 treatment groups
Group A: ControlNo intervention 0 interventions
Group B: Intervention groupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Number of patients that attend to the postpartum OGTT

Impact of electronic messages in the attendance rate of postpartum women with GDM at the TOTG-75g exam between 6 and 12 weeks after delivery

Time frame
From enrollment to the end of the recommended timeframe for postpartum OGTT (6 to 12 weeks after delivery)

Secondary outcomes

1

Dysglycemia rate according to diagnostic set of criteria

Compare the prevalence of prediabetes and diabetes in the postpartum period according to two diagnostic strategies applied to the 75g OGTT: Strategy A (currently in use): fasting blood glucose measurements and measurements two hours after glucose loading Strategy B (under investigation): fasting blood glucose measurements and measurements one hour after glucose loading

Time frame
From enrollment to OGTT test (6 to 12 weeks after delivery)

Other outcomes

Sponsors and contacts

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