In France, only the fasting blood glucose (FBG) measurement is recommended for diabetes screening. Ethnic heterogeneity and genetic polymorphisms specific to the Afro-Caribbean and Indo-Caribbean population in Guadeloupe justify the interest to early screen type 2 diabetes mellitus (T2DM). Our main objective is to estimate the prevalence of T2DM defined by oral glucose tolerance (OGTT) in subjects with risk factors for T2DM and not diagnosed with the FBG.
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Single group
After inclusion, the subjects will have an OGTT performed in the department of Diabetology. If the glucose blood levels remain normal after the OGTT, the test will be repeated after 12 months. A contr
Diagnostic testAfter inclusion, the subjects will have an OGTT performed in the department of Diabetology. If the glucose blood levels remain normal after the OGTT, the test will be repeated after 12 months. A control of the HbA1c levels will be also performed associated with a physical examination.
HbA1c levels > 5.7%,
Percentage of patients with HbA1c levels \> 5.7%, who exceeded the glucose threshold of 11mmol/L (200mg/dL), 2 hours after the oral glucose toleranceand who were not diagnosed with fasting blood glucose
diabetic and non-diabetic subjects according to oral glucose tolerance
Percentage of diabetic and non-diabetic subjects according to OGTT by age, gender, presence of metabolic syndrome, ethnic origin and biological data
explanatory factors
Odd-ratio of explanatory factors for T2DM defined by the OGTT
type 2 diabetes mellitus after 1 year
Percentage of non-diabetic subjects who develop a T2DM after 1 years of follow-up.
fasting blood glucose
Sensitivity, specificity, positive and negative predictive value of fasting blood glucose after 1 year
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