SEDentary Lifestyle, Mortality and Major Adverse Clinical Outcomes in Chronic KIDney Disease

ConditionsChronic Kidney Disease Cardiovascular Diseases Frailty

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age40+

SponsorTurku University Hospital

About this trial

The goal of this study is to learn if a simple home exercise program can benefit patients with advanced chronic kidney disease. There is also an observational part of the study without an exercise program.

The study will record patients' mortality, cardiovascular events, emergency department visits, hospital stays, need for dialysis and 6 minutes walking distance. Also maximal oxygen uptake, quality of life and bone fractures are recorded and blood tests and X-rays analyzed. The prospective observational part of the study will investigate the link between cardiovascular and kidney health as well as exercise capacity and adverse outcomes.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age >40 years

Estimated glomerular filtration rate < 20ml/min/1.73m2 (CKD stage 4-5)

Informed consent from the patient is received

Disqualifiers

Maintenance dialysis dependency before inclusion

Pregnant women

Patient's lack of commitment to follow-up

Chronic or acute clinical condition with a prognosis less than 6 months

Trial design

Design model

Parallel

Treatments tested in this trial

EXERCISE TRAINING WITH OR WITHOUT MEDICATION
Behavioral
Single appointment with a registered physiotherapist educating the patient for rehabilitating physical training and exercise to be performed independently and regularly by the patient at home, minimum of three times a week, during the study period.

Treatment groups

400 Participants

are divided into 2 treatment groups

Group A: Exercise ProgramExperimental treatment 1 intervention

Group B: Standard of CareNo intervention 0 interventions