Segmental Lung Recruitment: a Randomized Controlled Trial
ConditionSegmental Lung Atelectasis
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorClinical Hospital Center Rijeka
About this trial
This study compares two ways of reopening collapsed parts of the lung in patients on a ventilator.
In one group, doctors use a small camera (bronchoscope) to guide air pressure directly to the blocked part of the lung. In the other group, increased air pressure is applied to the whole lung using the ventilator.
Patients are carefully monitored to ensure safety.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
treatment in ICU, presence of radiologically or clinically confirmed pulmonary atelectasis during ICU treatment, requirement for mechanical ventilation
Disqualifiers
primary or secondary lung malignancy
Trial design
Design model
Parallel
Treatments tested in this trial
Segmental lung recruitment
Procedure/SurgeryPatients will undergo bronchoscopy-guided targeted segmental lung recruitment via endobronchial blocker. Flexible bronchoscope will be introduced through the endotracheal tube and advanced under direct visualization to the affected lung segment. The endobronchial blocker will be positioned to temporarily occlude the segmental bronchus, creating a closed system. Sustained positive pressure of 30 cmH₂O will be applied directly to the atelectatic segment for 30 minutes, while standard ventilator settings will be maintained for the remaining lung tissue.
Conventional lung recruitment
Procedure/SurgeryPatients in the control group received standard recruitment maneuvers consisting of continuous positive airway pressure (CPAP) of 40 cmH₂O applied to the entire respiratory system for 40 seconds. This approach represents the conventional recruitment strategy used in clinical practice.
Treatment groups
20 Participants
are divided into 2 treatment groupsGroup A: Segmental lung recruitmentExperimental treatment 1 intervention
Group B: Control groupActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Safety profile
The primary safety outcomes will be the incidence of clinically significant desaturation and hemodynamic instability during and within 30 minutes following the recruitment.
Time frame
From enrollment 72 hoursLocations
Sponsors and contacts
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Source ClinicalTrials.gov
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