About this trial
Subtle speech disorganization could be predictive of a transition to schizophrenia of ultra-high-risk patients. The aim of our longitudinal multicenter cohort study is to identify specific linguistic markers of the psychotic transition to validate a french predictive model of this transition using computerized speech analysis techniques
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Major and/or minor from 15 to 30 years old
Who alleged a suicidal gesture or idea or behavior that has repercussions in their emotional, social or professional life
If patients receive neuroleptic treatment that impairs cognitive abilities, a one-week wash-out period will be scheduled prior to assessment.
Affiliated with or beneficiary of a health insurance/social security system
Disqualifiers
History of psychosis
Risk of self-harm or violence not compatible with outpatient treatment
QI<70 (WAIS)
Neurological disorder or major health problem
Trial population
Help-seekers patients are recruited during two years from the early psychosis detection centers in Brest, France (CEVUP), Paris, France (CJAAD) and in Lausanne, Switzerland
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Transition to schizophrenia
Determined from the CAARMS scale (COMPREHENSIVE ASSESSMENT OF AT RISK MENTAL STATES)
Secondary outcomes
Identification of patients at "ultra high risk " for developing schizophrenia
Determined from the CAARMS scale ( COMPREHENSIVE ASSESSMENT OF AT RISK MENTAL STATES)
Sponsors and contacts
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