Semantic and Syntactic Computerized Analysis of Free Speech

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age15-30
SponsorUniversity Hospital, Brest

About this trial

Subtle speech disorganization could be predictive of a transition to schizophrenia of ultra-high-risk patients. The aim of our longitudinal multicenter cohort study is to identify specific linguistic markers of the psychotic transition to validate a french predictive model of this transition using computerized speech analysis techniques

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Major and/or minor from 15 to 30 years old

Who alleged a suicidal gesture or idea or behavior that has repercussions in their emotional, social or professional life

If patients receive neuroleptic treatment that impairs cognitive abilities, a one-week wash-out period will be scheduled prior to assessment.

Affiliated with or beneficiary of a health insurance/social security system

Disqualifiers

History of psychosis

Risk of self-harm or violence not compatible with outpatient treatment

QI<70 (WAIS)

Neurological disorder or major health problem

Trial population

Help-seekers patients are recruited during two years from the early psychosis detection centers in Brest, France (CEVUP), Paris, France (CJAAD) and in Lausanne, Switzerland

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Transition to schizophrenia

Determined from the CAARMS scale (COMPREHENSIVE ASSESSMENT OF AT RISK MENTAL STATES)

Time frame
2 years

Secondary outcomes

1

Identification of patients at "ultra high risk " for developing schizophrenia

Determined from the CAARMS scale ( COMPREHENSIVE ASSESSMENT OF AT RISK MENTAL STATES)

Time frame
Day 0

Other outcomes

Sponsors and contacts

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