Sensitivity to Ovarian Hormones and Depression in Adolescents
ConditionDepressed
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age12-18
SponsorUniversity of Calgary
About this trial
The goal of this observational study is to learn about the relationship between changes in ovarian hormones (estrogen and progesterone) and adolescent depression. The main question it aims to answer is:
Can we identify a subset adolescents assigned female at birth with a history of depression who are particularly sensitive to changes in ovarian hormones? Participants will be monitoring daily absolute ovarian hormone levels at home using the Mira Analyzer and answer online survey questions about their mental health for 90 days.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Assigned female at birth, at least 1 year post-menarche, naturally cycling, history of depression or symptoms of depression, and able to read and write in English.
Disqualifiers
Pregnant or taking any hormonal or cycle altering medications/devices.
Trial population
Depressed, naturally cycling adolescents assigned female at birth.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
94 Participants
are grouped into 1 trial groupGroup A: SOHDA corort
Trial outcomes
Primary outcomes
1
Identification ovarian hormone affect sensitivity
Identify depressed adolescents assigned female at birth with depressed affect sensitivity to changes in ovarian hormones across the menstrual cycle.
Time frame
90 daysSponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: