Serratus Posterior Superior Intekcostal Plane Block vs Serratus Anterior Plane Block for Postoperative Analgesia in VATS: A Randomized Trial"

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorSamsun University

About this trial

Thoracotomy is known as one of the most painful surgical procedures, with up to 65% of patients developing chronic post-thoracotomy pain syndrome (PTPS), and approximately 10% experiencing pain that significantly impacts quality of life. Video-assisted thoracoscopic surgery (VATS) has become increasingly common over the past decade and offers reduced postoperative pain, morbidity, and length of hospital stay compared to open thoracotomy. However, VATS can still cause moderate to severe postoperative pain and a high risk of chronic pain. Optimizing analgesia after VATS remains critical. With advances in ultrasound technology, several regional anesthesia techniques such as serratus anterior plane block (SAPB), erector spinae plane block (ESPB), and thoracic epidural analgesia (TEA) have shown comparable efficacy. In 2023, Tulgar et al. described the serratus posterior superior intercostal plane block (SPSIPB), which demonstrated dermatomal coverage from C3 to T10. This randomized controlled trial aims to compare the analgesic efficacy of SPSIPB and SAPB in patients undergoing VATS procedures.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

BMI < 35 kg/m² Patients with ASA scores I, II, III

Disqualifiers

Patients who do not want to be included in the study Psychiatric and neurological disease with blurred consciousness Patients with ASA > 3 BMI > 35 kg/m² Abnormality in coagulation parameters History of allergy to local anesthetic drugs Infection at the injection site Patients whose surgical procedure time exceeds 150 minutes

Trial design

Design model

Parallel

Treatments tested in this trial

  • SAPB

    Other intervention

    Ultrasound guided serratus anterior plane block will be performed.

  • SPSIPB

    Other intervention

    Ultrasound guided serratus posterior superior intercostal plane block will be performed.

Treatment groups

50 Participants
are divided into 2 treatment groups
Group A: group serratus anterior plane block (SAP)Active comparator 1 intervention
Group B: group serratus posterior superior intercostal plane block(SPSIP)Active comparator 1 intervention

Trial outcomes

Primary outcomes

1

Morphine consumption in the first 24 hours postoperatively

Morfin consumption in the first 24 hours after surgery

Time frame
up to 24 hours

Secondary outcomes

1

Pain density

NRS scores (Numeric rating scale; 0: no pain, 10: severe pain) in the first 24 hours after surgery

Time frame
up to 24 hours.
2

Quality of recovery

QR15 scores

Time frame
24 hours after surgery
3

Nausea and vomiting

Nausea and vomiting scores in the first 24 hours (verbal rating scale; 0= none, 1= nausea, 2= gagging, 3= vomiting)

Time frame
up to 24 hours
4

shoulder pain

postoperative shoulder pain;shoulder pain will be evaluated as present/absent

Time frame
up to 24 hours

Other outcomes

Sponsors and contacts

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