Serum Calprotectin in Surgical Septic Patients
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAzienda Ospedaliero, Universitaria Pisana
About this trial
To early evaluate the serum levels of calprotectin in patients suffering from intra-abdominal sepsis requiring a surgical treatment. The research project aims to investigate the role of serum calprotectin in the diagnosis of sepsis and to establish whether its level significantly correlates with different degree of disease severity and with short and long-term outcomes. If these associations were confirmed, serum calprotectin would represent an easily and rapidly detectable biomarker able to predict the severity of sepsis.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
diagnosis of upper/lower gastro-intestinal perforation
diagnosis of intestinal occlusion
diagnosis of acute cholecystitis
diagnosis of complicated acute appendicitis
Disqualifiers
recent (<3 months) surgery
recent (<3 months) trauma
diagnosis of acute pancreatitis
diagnosis of burn
Trial population
Septic patients requiring surgery at the Department of General and Emergency Surgery of the University of Pisa
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
serum calprotectin
Diagnostic testA blood sample is collected at time of admission to detect serum level of calprotectin
Treatment groups
150 Participants
are divided into 3 treatment groupsGroup A: Group A1 intervention
Group B: Group B1 intervention
Group C: Group C1 intervention
Trial outcomes
Primary outcomes
1
Sepsis detection
We'll measure the serum calprotectin level in enrolled patients of the two groups (group A and B) and in patients of the control group.
Time frame
admissionSponsors and contacts
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Source ClinicalTrials.gov