Health TrialsbyHealthPanel

Serum EBI-3 Protein Levels in Behçet's Disease

ConditionBehçet Disease
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssiut University

About this trial

This cross-sectional study aims to evaluate serum Epstein-Barr virus-induced gene 3 (EBI-3) protein levels in patients with Behçet's disease compared with healthy controls.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

- Age 18 years or older

Diagnosis of Behçet's disease according to the International Criteria for Behçet's Disease (cases)

Healthy individuals without autoimmune or inflammatory diseases (controls)

Written informed consent

Disqualifiers

- Other autoimmune disorders (RA, SLE, psoriatic arthritis, ankylosing spondylitis)

Acute or chronic infection

Malignancy or history of malignancy

Chronic liver disease or advanced chronic kidney disease

Trial population

Adult patients with Behçet's disease attending the Physical Medicine, Rheumatology and Rehabilitation Department at Assiut University Hospitals, and healthy controls.

Trial design

Design model

Case-control

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

90 Participants
are grouped into 2 trial groups
Group A: Behçet's Disease
Group B: Healthy Controls

Trial outcomes

Primary outcomes

1

Mean serum EBI-3 protein level

Mean serum Epstein-Barr virus-induced gene 3 (EBI-3) protein concentration measured by ELISA in patients with Behçet's disease compared with healthy controls.

Time frame
Baseline

Secondary outcomes

1

Serum EBI-3 level according to disease activity

Mean serum EBI-3 protein concentration according to Behçet's Disease Current Activity Form (BDCAF) score.

Time frame
Baseline
2

Serum EBI-3 level in patients with vascular involvement

Mean serum EBI-3 protein concentration in patients with and without vascular involvement

Time frame
Baseline
3

Serum EBI-3 level in patients with ocular involvement

Mean serum EBI-3 protein concentration in patients with and without ocular involvement.

Time frame
Baseline
4

Serum EBI-3 level in patients with neurological involvement

Mean serum EBI-3 protein concentration in patients with and without neurological involvement.

Time frame
Baseline

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assiut University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: