Health TrialsbyHealthPanel

Serum Soluble BCMA as a Non-Invasive Marker in Multiple Myeloma

ConditionMultiple Myeloma
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssiut University

About this trial

This prospective study aims to investigate serum soluble B-cell maturation antigen (sBCMA) as a non-invasive marker in patients with multiple myeloma and to compare its levels with healthy controls.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age 18 years or older

Newly diagnosed multiple myeloma according to WHO 2022 criteria

Pretreatment at time of sample collection

Age 18 years or older

Disqualifiers

- Other active malignancies or autoimmune diseases

Severe renal impairment (serum creatinine > 3.0 mg/dL)

Active infection or inflammatory disease at sampling

Pregnancy or lactation

Trial population

Patients with multiple myeloma and healthy controls attending South Egypt Cancer Institute, Assiut University.

Trial design

Design model

Case-only

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

90 Participants
are grouped into 3 trial groups
Group A: Newly Diagnosed Multiple Myeloma
Group B: Relapsed/Refractory Multiple Myeloma
Group C: Healthy Controls

Trial outcomes

Primary outcomes

1

Mean serum soluble BCMA level

Mean serum soluble B-cell maturation antigen (sBCMA) concentration measured by ELISA in ng/mL.

Time frame
Baseline

Secondary outcomes

1

Mean serum soluble BCMA in newly diagnosed multiple myeloma

Mean serum sBCMA level in newly diagnosed multiple myeloma patients.

Time frame
Baseline
2

Mean serum soluble BCMA in relapsed/refractory multiple myeloma

Mean serum sBCMA level in relapsed or refractory multiple myeloma patients.

Time frame
Baseline
3

Mean serum soluble BCMA in healthy controls

Mean serum sBCMA level in healthy control subjects.

Time frame
Baseline
4

Mean hemoglobin level

Mean hemoglobin concentration in g/d

Time frame
Baseline

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assiut University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: