Shift Hours' Impact on Fatigue and Tracking of Eye Dynamics

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorIMADIS Technologies et Services

About this trial

The goal of this clinical trial is to learn how night shift-induced sleep debt affects oculomotor patterns, attentional state, and diagnostic performance in emergency radiologists.

The main questions it aims to answer are:

* Does sleep debt from a night shift alter oculomotor parameters, as eyes movements (speed and amplitude), fixation duration, pupil size? * Does a night shift impact radiologists' diagnostic accuracy, attentional state, and perceived fatigue? Researchers will compare radiologists after a night shift (sleep-deprived) with the same radiologists after a night of rest (control) to see if fatigue-related changes affect both visual exploration strategies and diagnostic performance.

Participants will:

* Perform a guided saccade task assessed by eye tracking (primary endpoint), * Read thoracic CT scans (with and without pulmonary embolism cases) to assess diagnostic performance and visual exploration patterns, * Undergo EEG recording to measure attentional state, * Complete self-report questionnaires on sleepiness and fatigue.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

In their current position for at least one year

Working at one of the IMADIS Group on-call centers

Performing night shifts during the study period

Able to wear an actimeter watch during the study period (it may be removed during certain procedures, but must be put back on afterwards)

Disqualifiers

None

Trial design

Design model

Single group

Treatments tested in this trial

  • Electroencephalogram

    Device

    EEG measurement to assess attentional state

  • Actigraphy

    Device

    Evaluation of sleep-wake phases 24 hours prior to eye tracking measurement

  • Eye Tracking

    Device

    Assessment of ocular parameters during controlled eye tracking: guided saccade task followed by analysis of chest scans to detect pulmonary embolism. Measurement of ocular saccade parameters (distance, velocity), fixation time and pupil diameter. Measurements performed twice: after a night on call and after a night of rest.

  • Questionnaires

    Other intervention

    Measurements of sleepiness (Karolinska Sleep Scale KSS, Epworth Sleep Scale ESS), mental fatigue (EVA Scale), insomnia (Insomnia Severity Index, ISI) and chronotype (Morningness Eveningness Questionnaire, MEQ) * Inclusion visit: MEQ * Before the first evaluation: ISI, KSS, ESS, EVA * Before the second evaluation: ISI, KSS, ESS, EVA

Treatment groups

40 Participants
are divided into 1 treatment group
Group A: Study cohortExperimental treatment 4 interventions

Trial outcomes

Primary outcomes

1

Comparison of slope of the relationship between maximum speed and saccade magnitude

Slope of the relationship between maximum saccadic speed and saccade magnitude This parameter reflects the dynamics of saccadic eye movements. It is derived from the main sequence, which describes the linear relationship between the amplitude of a saccade (in degrees of visual angle) and its maximum velocity (in degrees per second). The slope quantifies how rapidly maximum saccadic speed increases with increasing saccade magnitude. A steeper slope indicates faster oculomotor responses for larger saccades, whereas a reduced slope may reflect fatigue, reduced alertness, or impaired oculomotor function.

Time frame
Comparison of measurement obtained during an 8-minute guided saccade task during the two measurement phases : after a night call and after a night's rest

Secondary outcomes

1

Comparison of duration of fixations on areas of interest, in milliseconds

Eye tracking measurement performed on pulmonary embolism examination readings. Fixation time measured on areas of interest defined on each examination.

Time frame
Comparison of measurements taken on the morning after a night shift and on the morning after a night of rest
2

Comparison of percent of embolisms detected

Measurement during the reading of chest scans. Information collected using the "logbook" and compared to the gold standard.

Time frame
Comparison of measurements taken on the morning after a night shift and on the morning after a night of rest
3

Comparison of pupil diameter

Pupil diameter measured using eye tracking during the guided saccade task

Time frame
Comparison of measurements taken on the morning after a night shift and on the morning after a night of rest
4

Comparison of attentional systems

EEG measurement of different brain waves (Theta, Alpha, Beta, and Gamma activities) representative of the attentional system.

Time frame
Comparison of measurement taken on the morning after a night shift and on the morning after a night of rest

Other outcomes

1

Sleep-wake cycle over the last 24 hours

Measurement taken to determine the subjects' sleep-wake cycle during the 24 hours preceding each measurement. Assessment of the number of hours slept in order to normalize the data during analysis, determined by actimetric measurement

Time frame
Measurements taken 24 hours before each measurement phase (night shift and a night of rest)

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

IMADIS Technologies et Services

Lead sponsor

Lyon Neuroscience Research Center (CRNL)

Collaborator

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