A combined prospective cohort study and retrospective analysis of previously collected data. Three different techniques for posterior lumbar interbody fusion (PLIF) are compared: CBT-PLIF, MI-PLIF and open PLIF. A total of 180 patients are included, who will be followed up to 6 weeks postoperatively.
18-75 years
Degenerative or spondylolytic spondylolisthesis
Neurogenic claudication and/or radicular leg pain
Low grade (Meyerding grade l and ll)
Previous spine fusion surgery at the same level
Osteoporosis
Active infection or prior infection at the surgical site
Active cancer
A total of 180 participants, 60 prospective CBT-PLIF participants, 60 retrospective open-PLIF and 60 retrospective MI-PLIF participants. Patients aged 18-75 years with neurogenic claudication and/or radicular leg pain due to a low grade (Meyerding grade l and ll) degenerative or spondylolytic spondylolisthesis with persistent complaints for over 3 months will be included in the study. Patients are operated in either the University Medical Centre Groningen (UMCG) or in the Haaglanden Medical Centre (HMC).
Cohort
Other
Posterior Lumbar Interbody Fusion (PLIF)
Procedure/SurgerySpinal fusion in the lumbar spine by inserting a cage directly into the disc space. This is an observational study in which the standard procedure/care is followed.
VAS low back pain
VAS for low back pain ranging from 0mm (no pain) to 100mm (worst pain imaginable)
VAS low back pain
VAS for low back pain ranging from 0mm (no pain) to 100mm (worst pain imaginable)
VAS leg pain
VAS for leg pain ranging from 0mm (no pain) to 100mm (worst pain imaginable)
Oswestry Disability Index
Used to quantify the degree of functional impairment in patients with low back pain. Ranging from 0 (no disability) to 100 (bed bound)
Quality of Life (QoL)
Measured by the EQ-5D-5L
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Jos M. A. Kuijlen
Lead sponsor
University Medical Center Groningen
Sponsor institution
