About this trial
Research is to compare and evaluate the clinical and radiographic outcomes of the enamel matrix derivative with or without connective tissue wall graft for noncontained infrabony defects using simplified papilla preservation technique .
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Patients willing to participate in the study.
Participants aged ≥18 years to 55 years.
Presented with non contained infra bony defects.
Presence of at least 1 non contained infra bony defect(IBD) with a pocket probing depth ≥6mm after reevaluation of the hygienic phase and a depth of IBD ≥3mm as detected on radiographs, with radiographic angulation of ≥37⸰ , and exhibiting a 1 or 2 wall infra bony defect15(assessed by a bone sounding and confirmed intrasurgically)
Disqualifiers
Grade III mobility, endodontically treated teeth.
Pregnant and lactating females.
History of tobacco smoking .
Patients with systemic disease.
Trial design
Parallel
Treatments tested in this trial
Enamel matrix derivative
Procedure/Surgeryconnective tissue graft and Enamel matrix derivative in the defect area
Treatment groups
Trial outcomes
Primary outcomes
clinical attachment gain
change in attachment level for patient with isolated 2 or 3 wall defect treated with enamel matrix derivative and connective tissue wall graft in 1,3 and 6 months follow up
Secondary outcomes
pocket probing depth
change in pocket probing depth from baseline to 1,3 and 6 months
radiographic bone gain
change in radiographic bone level from baseline to 1,3,6 months
recession reduction
change in recession from baseline to 1,3 and 6 months
plaque index
change in plaque index from baseline to 1,3 and 6 months
Locations
Sponsors and contacts
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