Brief Summary
The goal of this observational study is to learn how environmental factors, lifestyle choices, and social conditions affect the timing of menopause in Asian women aged 40-50 years living in Singapore. The main aims of the project are the following:
* Do environmental pollutants and lifestyle exposures contribute to earlier menopause in Asian women? * What biological changes occur when women are exposed to harmful environmental factors during menopause transition?
Participants will be followed for 18 months and will complete questionnaires about their health history, lifestyle, diet, and environmental exposures. Participants will provide blood, urine, stool, hair, and nail samples for laboratory analysis and undergo basic health assessments including weight, blood pressure, and bone density measurements. Participants will wear activity monitors and air pollution sensors for 7 days and attend follow-up visits at 6 months, 12 months, and 18 months to track changes in their health. This data will be obtained during the baseline visit.
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Women experiencing perimenopausal transition characterized by irregular menstrual patterns and hormonal fluctuations, stratified by age groups (40-45 years and 46-50 years) and ethnicity to ensure representative sampling of Singapore's multi-ethnic population.
Cohort
Prospective
Not listed
Early menopause
Time to menopause onset
• Menopausal symptom severity score using standardized assessment tools
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This trial is not recruiting at the moment. You can still explore other options:
