About this trial
Reducing intra- and postoperative pain or using less opioids is an essential strategy in today's operations. One emerging and widely used method in this context is the use of preemptive analgesic medication. Paracetamol and ibuprofen used preemptively have been shown to reduce postoperative opioid use and pain scores. There are also studies showing that preemptive analgesia with different analgesic medications reduces opioid consumption and postoperative pain. Our study will evaluate both the intraoperative and postoperative effectiveness of paracetamol and ibupurofen with preemptive analgesia, considering total opioid use. It will also investigate drug side effects and their advantages using a 15-question compilation quality scale, validated in Turkish.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Septorhinoplasty surgery
ASA1-2 patients
Men and women aged 18-65
Informed consent and acceptance to participate in the study
Disqualifiers
ASA 3-4 and under 18 years of age
Patients with serious renal, hepatological, cardiovascular, or pulmonary system diseases
Allergy to paracetamol or ibuprofen
Patients with bleeding diathesis, platelet dysfunction, GI disease, peptic ulcers, pregnancy, planning pregnancy, and breastfeeding mothers
Trial population
PATIENTS UNDERGOING SEPTORINOPLASTY SURGERY
Trial design
Other
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
ANALGESIA
24-HOUR CUMULATIVE OPIOID CONSUMPTION
COMPILATION
POSTOPERATIVE QUALITY OF RECOVERY-15 SCALE
PAIN SCORE
PAIN WILL BE ASSESSED POSTOPERATIVELY AT 0, 1, 6, 12, and 24 HOURS, BOTH AT REST AND DURING ACTIVITY (COUGHING AND DEEP BREATHING), USING THE NRS (Numeric Rating Scale).
Sponsors and contacts
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