Single Dose Preemptive Paracetamol or Ibuprofen Before Septrorhinoplasty on Intra- and Postoperative Opioid Consumption.

ConditionAnalgesia
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorSamsun University

About this trial

Reducing intra- and postoperative pain or using less opioids is an essential strategy in today's operations. One emerging and widely used method in this context is the use of preemptive analgesic medication. Paracetamol and ibuprofen used preemptively have been shown to reduce postoperative opioid use and pain scores. There are also studies showing that preemptive analgesia with different analgesic medications reduces opioid consumption and postoperative pain. Our study will evaluate both the intraoperative and postoperative effectiveness of paracetamol and ibupurofen with preemptive analgesia, considering total opioid use. It will also investigate drug side effects and their advantages using a 15-question compilation quality scale, validated in Turkish.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Septorhinoplasty surgery

ASA1-2 patients

Men and women aged 18-65

Informed consent and acceptance to participate in the study

Disqualifiers

ASA 3-4 and under 18 years of age

Patients with serious renal, hepatological, cardiovascular, or pulmonary system diseases

Allergy to paracetamol or ibuprofen

Patients with bleeding diathesis, platelet dysfunction, GI disease, peptic ulcers, pregnancy, planning pregnancy, and breastfeeding mothers

Trial population

PATIENTS UNDERGOING SEPTORINOPLASTY SURGERY

Trial design

Design model

Other

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

54 Participants
are grouped into 3 trial groups
Group A: GROUP P
Group B: GROUP I
Group C: GROUP K

Trial outcomes

Primary outcomes

1

ANALGESIA

24-HOUR CUMULATIVE OPIOID CONSUMPTION

Time frame
24 HOURS
2

COMPILATION

POSTOPERATIVE QUALITY OF RECOVERY-15 SCALE

Time frame
POSTOPERATIVE 24TH HOUR
3

PAIN SCORE

PAIN WILL BE ASSESSED POSTOPERATIVELY AT 0, 1, 6, 12, and 24 HOURS, BOTH AT REST AND DURING ACTIVITY (COUGHING AND DEEP BREATHING), USING THE NRS (Numeric Rating Scale).

Time frame
24 HOURS

Secondary outcomes

Other outcomes

Sponsors and contacts

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