Single-Incision Gasless Endoscopic Total Thyroidectomy Via Subclavian Approach Versus Open Surgery for PTC

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorSun Yat-Sen Memorial Hospital of Sun Yat-Sen University

About this trial

Historically, performing a contralateral thyroid lobectomy and lymph node dissection via the subclavian approach was considered challenging. This study aimed to evaluate the safety and feasibility of single-incision gasless endoscopic total thyroidectomy and central compartment neck dissection via the subclavian approach (SCA) in comparison to conventional open surgery for the treatment of papillary thyroid carcinoma (PTC) retrospectively.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

(1) thyroid neoplasm <3.0 cm;

(2) well differentiated papillary thyroid carcinoma.

Disqualifiers

(1) extrathyroidal extensions estimated in ultrasonography scan;

(2) enlarged lymph nodes in lateral neck compartment on palpation, or US scan;

(3) suspected distant metastases;

(4) previous history of neck radiation therapy and/or surgery.

Trial population

The patients, who were diagnosed with papillary thyroid carcinoma at our center, chose to undergo either single-incision, gasless endoscopic total thyroidectomy with central compartment neck dissection via the subclavian approach or conventional open surgery.

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

  • single-incision, gasless endoscopic total thyroidectomy with central compartment neck dissection

    Procedure/Surgery

    The included patients chose to undergo single-incision, gasless endoscopic total thyroidectomy with central compartment neck dissection via the subclavian approach based on patients preference.

  • conventional open surgery

    Procedure/Surgery

    These patients chose to undergo total thyroidectomy with central compartment neck dissection via conventional open surgery based on patients preference.

Treatment groups

120 Participants
are divided into 2 treatment groups
Group A: the Subclavian Approach group1 intervention
Group B: the conventional open surgery group1 intervention

Trial outcomes

Primary outcomes

1

the disease-free survival

The disease-free survival refers to the probability of survival without any biologic, structural, or functional events.

Time frame
up to 24 months

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.