Site Preservation After Tooth Extraction
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-60
SponsorNanfang Hospital, Southern Medical University
About this trial
This study is mainly targeted affected teeth which could not be retained, and patients are willing to undergo implant repair at the later stage. After teeth extraction, Geistlich Bio-Oss ® Particles or Bio-Oss ® Collagen are immediately implanted in the teeth extraction socket and covered with Bio-Gide ® collagen membrane for site preservation.Through postoperative follow-up, postoperative clinical and imaging objective indicators, combined with the subjective evaluation of surgeons and patients, and compared with conventional extraction treatment method, the study is aimed to evaluate the effectiveness of different site preservation of alveolar crest preservation, in order to reduce the alveolar bone width and height loss, effectively reduce alveolar bone absorption, or even achieve bone incrementation, thus to get the ideal site preservation effect, to improve the oral implant success rate, improve implant aesthetic score and patient satisfaction, provide more clinical standard reference of the clinical application of site preservation.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
patients willing to performed site preservation with Geistlich Bio-Oss ® Particles + Bio-Gide ® collagen membrane after tooth extraction;
patients willing to performed site preservation with Geistlich Bio-Oss ® Collagen + Bio-Gide ® collagen membrane after tooth extraction;
patients willing to performed no site preservation after tooth extraction and only conventional healing.
Disqualifiers
patients unwilling to sign the informed consent form and the letter of authorization;
patients has a potential systematic diseases;
patients had previously been treated with radiation therapy;
patients can not re-visit on time.
Trial population
Patients who have teeth cannot be retained and are willing to do dental implant treatment at the teeth extration site.
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
88 Participants
are grouped into 3 trial groupsGroup A: Geistlich Bio-Oss ® Particles + Bio-Gide ® collagen membrane
Group B: Geistlich Bio-Oss ® Collagen + Bio-Gide ® collagen membrane
Group C: Conventional healing after tooth extraction, without site preservation
Trial outcomes
Primary outcomes
1
Changes in the alveolar crest height - central
The central alveolar bone height of the ideal implant site will be measured with CBCT at 3 months after tooth extraction or plus site preservation
Time frame
up to 12 weeks after Dental extraction or site preservation surgery2
Changes in the alveolar crest width - central
The central alveolar bone width of the ideal implant site will be measured with CBCT at 3 months after tooth extraction alone or plus site preservation
Time frame
up to 12 weeks after Dental extraction or site preservation surgerySecondary outcomes
1
Changes in the alveolar bone width - different depths
The width of the alveolar bone at 1,3,5, and 7mm below the alveolar crest will be measured with CBCT at 3 months after tooth extraction or plus site preservation
Time frame
up to 12 weeks after Dental extraction or site preservation surgery2
Changes in the alveolar bone height - different horizontal sites
The height of the alveolar bone will be measured at the mesial, central and distal of buccal and lingual of alveolar crest,and the midpoint of the mesial and distal of interproximal sites with CBCT at 3 months after tooth extraction alone or plus site preservation
Time frame
up to 12 weeks after Dental extraction or site preservation surgery3
Soft tissue thickness
The thickness of soft tissue will be measured at middle, central, and distal sites of both buccal-lingual sides,3mm from free gingival margin
Time frame
up to 12 weeks after Dental extraction or site preservation surgery4
Plaque index (PLI)
Each tooth extraction socket will be measured on 6 sites: buccal, central and lingual of both mesial-distal sides
Time frame
up to 12 weeks after Dental extraction or site preservation surgeryLocations
Sponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: