Sleep Disordered Breathing, Endothelial Function, and Adverse Events in Pregnancy
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorUniversity of Alberta
About this trial
This is a prospective longitudinal cohort study whereby pregnant individuals are asked to complete an 8-day testing protocol to measure their sleep and cardiovascular health at two timepoints during pregnancy.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
over 18 years of age
pregnant (20-24 weeks gestation at enrollment)
Disqualifiers
worked shift work past 11pm in the previous month
previously diagnosed with a sleep disorder by a physician
Trial population
Pregnant individuals with and without symptoms of sleep disordered breathing.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Endothelial Function
The investigators will assess endothelial function using flow mediated dilation
Time frame
20-24 weeks and 28-36 weeks gestationSecondary outcomes
1
Cardiovascular Function - arterial stiffness with pulse wave velocity
The investigators will measure arterial stiffness using pulse wave velocity of the carotid and femoral arteries
Time frame
20-24 weeks and 28-36 weeks gestation2
Cardiovascular Function - arterial stiffness with beat-by-beat blood pressure
The investigators will measure arterial stiffness using beat-by-beat blood pressure from the finger.
Time frame
20-24 weeks and 28-36 weeks gestation3
Cardiovascular Function - ambulatory blood pressure
Blood pressure will be collected every 30 minutes during a 24-hour period using an ambulatory blood pressure monitor.
Time frame
20-24 weeks and 28-36 weeks gestation4
Cardiovascular Function - resting blood pressure
Beat-by-beat blood pressure will be collected at rest.
Time frame
20-24 weeks and 28-36 weeks gestationSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov