About this trial
Epilepsy, a prevalent neurological disorder, affects 40% of patients with uncontrolled seizures despite medications. Sleep disturbance exacerbates epilepsy, and vice versa, but existing literature suffers from limitations. Studies conducted in hospital settings provide only brief observation periods and fail to capture the natural sleep environment. Wearable technology offers a promising solution, providing a nuanced understanding of the relationship between seizures and sleep. The Dreem headband, an EEG-based wearable, is well-suited for such studies, offering ease of use and validated accuracy. This technology enables extended observation periods under stable medication conditions, essential for assessing the complex interplay between sleep and epilepsy. By elucidating the impact of sleep on seizures, the researchers seek to identify patient populations where sleep significantly influences seizure susceptibility, ultimately informing personalized epilepsy treatments.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age > 18 years
At least 2 seizures per week based on clinical notes
Patients where medications will stay stable over the study period
40% of both spikes and spindles are identifiable on the dreem headband based on the screening night
Disqualifiers
Cognitive impairment
Psychiatric comorbidities which may influence sleep
No bedpartner/caregiver to observe seizures
Low agreement (below 60%) between Dreem's sleep scoring and manual scoring will be excluded from the study
Trial design
Single group
Treatments tested in this trial
Dreem headband
DeviceThe Dreem headband is an EEG-based wearable tool that can be used to reliably assess the relationship between sleep and epilepsy over extended observation periods.
Treatment groups
Trial outcomes
Primary outcomes
Total sleep time (sleep macrostructure)
Total sleep time as measured by the Dreem headband
Spike rates per hour (epilepsy marker)
Spikes will be detected by the Dreem headband
Seizure frequency per night (epilepsy marker)
Seizures will be detected by the Dreem headband
Secondary outcomes
Sleep latency (sleep macrostructure)
Sleep latency as measured by the Dreem headband
Wake after sleep onset (sleep macrostructure)
Wake after sleep onset as measured by the Dreem headband
Sleep efficiency (sleep macrostructure)
Sleep efficiency as measured by the Dreem headband
Sleep stage distribution (sleep macrostructure)
Sleep stage distribution as measured by the Dreem headband
Sponsors and contacts
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