SLR-108 PET Imaging in Subjects With Metastatic Solid Tumors
ConditionMetastatic Solid Tumors
Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18+
SponsorSolve Therapeutics
About this trial
This is a Phase 1 study evaluating the feasibility of using SLR-108 for positron-emission tomography (PET) imaging of metastatic solid tumors.
Eligibility criteria
Qualifiers
Men or women (as appropriate for cancer type) of age ≥18 years.
Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1, or 2.
Histologically or cytologically confirmed diagnosis of solid tumor as documented in medical records.
Based on the most recent tumor assessment, presence of metastatic disease that has progressed during or following previous treatment.
Disqualifiers
Malignancy involving the central nervous system unless brain metastases have been previously treated with radiotherapy, have been stable for ≥4 weeks, and do not require corticosteroids.
Presence of another cancer with disease manifestations or therapy that could adversely affect subject safety or longevity, create the potential for drug-drug interactions, or compromise the interpretation of study results.
Uncontrolled ongoing systemic bacterial, fungal, or viral infection (including upper respiratory tract infection) at the time of study drug administration.
Significant cardiovascular event or comorbidity.
Trial design
Treatments tested in this trial
- SLR-108
- SLX-1411
Treatment groups
70 Participants
are divided into 5 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov