About this trial
The purpose of this research study is to examine the effect of social connectedness on the brain. Study procedures include one Magnetic Resonance Imaging (MRI) or functional Magnetic Resonance Imaging (fMRI) scan, one Positron Emission Tomography (PET) scan, one Magnetic Resonance Spectroscopy (MRS) scan, an electroencephalogram (EEG), and in-person and phone call follow-ups.
Eligibility criteria
Qualifiers
able to give written informed consent
age 55+
English speaking
Disqualifiers
contraindication to MRI scanning including claustrophobia, high girth, moderate to significant white matter atrophy, and presence of ferromagnetic material in the body, including orthodontic braces or other non MR-compatible foreign bodies. All participants will be screened for metal objects by the same methods used for routine clinical MRI scanning
for women: pregnancy or breastfeeding
serious medical or neurological illness that in the opinion of the PI would interfere with the scientific goals of the study or participant safety
pervasive developmental disorders (PDD) or primary psychotic disorders
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Sponsors and collaborators
Yale University
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator