Social Feedback and Dysfunctional Risk Taking in NSSI Adolescents

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age15-18
SponsorUniversity of Electronic Science and Technology of China

About this trial

Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Problematic interpersonal relationships and decision-making have been demonstrated to play crucial roles in this maladaptive behavior, especially for adolescents. Accumulating evidence suggests that decision processes and risk-taking are strongly influenced by the affective state of the individual. However, whether these interactions are disrupted in NSSI adolescents has not been systematically examined. In the current study, the investigators modified one of the most widely used paradigms for measuring an individual's risk decision-making, the Balloon Analogue Risk Task (BART). The investigators combine social reward (green balloon), punishment (red balloon), and control feedback (yellow balloon), to investigate whether the NSSI adolescents have dysfunctional risk-taking behavior while facing different social outcomes. The investigators recruit one group of NSSI adolescents (n = 40) and one health control (HC) group (n = 40), to compare their risk-related decisions during the emotional BART. The investigators hypothesize that compared to HC, NSSI adolescents will show altered effects of social reward and punishment on risk-related decision-making, in particular higher risk avoidance in the context of social punishment.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

15-18 years

right-handed

normal or corrected normal visual acuity

meet the proposed DSM-5 frequency criteria (e.g., ≥5 days of NSSI behaviors in the past year)

Disqualifiers

diagnosis of borderline personality disorder, major depressive disorder, other

psychiatric disorders, etc.

high suicidal risk

recent use of medications that can affect neural activity

Trial population

Treatment-seeking NSSI individuals will be recruited from local hospitals and HC from the community.

Trial design

Design model

Case-control

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

80 Participants
are grouped into 2 trial groups
Group A: NSSI
Group B: HC

Trial outcomes

Primary outcomes

1

Risky avoidance measured by BART

Adjusted number of pumps (average number of pumps excluding balloons that exploded) as the index of risk avoidance. Alterations in the patients will be determined by using ANOVA models with the group (NSSI vs. HC) as a between-subject factor and emotional feedback (social reward, social punishment, and control) as a within-subject factor.

Time frame
About 20 minutes
2

Decision-making measured by BART

Earned money (total amount of money earned in the task) as the index of decision-making. Alterations in the patients will be determined by using ANOVA models with the group (NSSI vs. HC) as a between-subject factor and emotional feedback (social reward, social punishment, and control) as a within-subject factor.

Time frame
About 20 minutes

Secondary outcomes

Other outcomes

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