The goal of this observational study is to identify behavioral and physiological markers of social alterations in Autism Spectrum Disorders compared to Typically Developping peers. This single-centre study plan to use eye tracking to evaluate social disorders in Autism Spectrum Disorders (ASD). The investigators will estimate oculometric and pupillometric indices as potential ASD biomarkers. The study will last 4 years and will be organized in two phases.
Age between 2 and 12 years
Group of children with ASD Age between 2 and 12 years Conformity with the diagnostic criteria of ASD according to DSM-V, ICD-10 or ICD-11
Group of children without TND : Age between 0 and 12 years
Group of adult subjects without ASD: Subject under guardianship or trusteeship Diagnosis of ASD Group of children without ASD : Diagnosis of ASD
Group of children with ASD ICD-10 diagnosis of PDD (Rett syndrome and Hayler syndrome) Phase 2
Group of children without ASD : Diagnosis of ASD (confirmed or ongoing)
Parallel
eye-tracker
Other interventionEye-tracker recordings of eye movements, gaze direction and pupillary reactivity
Oculometric measurements 1: Tracking time
Mean of tracking time (ms) during entire stimuli duration
Oculometric measurements 2: Fixation time on the screen
Mean of fixation time on the screen (ms) during entire stimuli duration
Oculometric measurements 3: Fixation time on the eye area during entire stimuli duration
Mean of fixation time on the eye area of face stimuli (ms) during entire stimuli duration
Oculometric measurements 4: Fixation time on the mouth area of face stimuli
Mean of fixation time on the mouth area of face stimuli (ms) during entire stimuli duration
Click on the lead sponsor to view all of their trials.
University Hospital, Tours
Lead sponsor
UMR 1253, iBrain, Université de Tours, Inserm, Tours, France.
Collaborator
Laboratory of Fundamental and Applied Computer Science of Tours, EA6300
Collaborator
National Research Agency, France
Collaborator
Ministry of Health, France
Collaborator
