SOFA-2 Score in Turkish ICUs
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorIzmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
About this trial
This study aims to evaluate how well a new scoring system called the Sequential Organ Failure Assessment-2 (SOFA-2) works in adult intensive care units in Türkiye.
SOFA-2 is designed to measure the severity of organ dysfunction in critically ill patients using routinely collected clinical and laboratory data. It is an updated version of the original SOFA score and reflects modern intensive care practices.
In this multicenter observational study, adult patients admitted to participating intensive care units will be followed during their ICU stay. SOFA and SOFA-2 scores will be calculated during the first 24 hours of admission, and in patients with longer stays, additional scores will be recorded. No additional tests or treatments will be performed as part of the study.
The main goal of the study is to examine the relationship between SOFA-2 scores and intensive care unit mortality. The results are expected to help clinicians better assess disease severity and outcomes in critically ill patients.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adults aged 18 years or older
Admission to a participating intensive care unit in Türkiye
Intensive care unit stay longer than 24 hours
Disqualifiers
Patients younger than 18 years
Pregnant patients
Organ donors
Patients with unknown intensive care unit discharge outcomes
Trial population
The study population consists of adult patients admitted to participating intensive care units across Türkiye. Eligible participants are critically ill adults who require intensive care monitoring and treatment and remain in the intensive care unit for more than 24 hours. The study includes a broad and heterogeneous ICU population reflecting routine clinical practice and does not target a specific dise
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
5,200 Participants
are grouped into 1 trial groupGroup A: Adult ICU Patients
Trial outcomes
Primary outcomes
1
Association Between 24-Hour SOFA-2 Score and ICU Mortality
The association between the total SOFA-2 score calculated within the first 24 hours of intensive care unit admission and all-cause ICU mortality. Higher scores show worse outcomes.
Time frame
60 days after ICU admissionSecondary outcomes
1
Reclassification Performance of SOFA-2 Compared With SOFA
Comparison of patient risk classification between SOFA and SOFA-2 scores with respect to ICU mortality.Higher scores show worse outcomes.
Time frame
60 days after ICU admissionSponsors and contacts
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Source ClinicalTrials.gov