Sonographic Parameters and Risk of Antepartum Hemorrhage in Asymptomatic Women With Placenta Previa: A Cohort Study

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
AgeNot listed
SponsorAin Shams University

About this trial

The aim of this study is to evaluate the effectiveness of ultrasonographic parameters (cervical length, placental thickness and distance placental edge from internal os of the cervix) in predicting the risk of antepartum hemorrhage and emergency cesarean delivery in asymptomatic women with placenta previa.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Asymptomatic women diagnosed with placenta previa according to RCOG (GTG No. 27a, 2018): placenta lies directly over the internal os for pregnancies more than 16 weeks' gestation on transabdominal or transvaginal scanning.

Gestational age between 28 till 37 weeks' gestation (as delivery should be considered between 36 and 37 weeks of gestation for women presenting with uncomplicated placenta previa)

Disqualifiers

Multiple pregnancies.

Threatened preterm labor or preterm rupture of membranes.

History of bleeding in the current pregnancy.

Polyhydraminos (AFI > 25 cm).

Trial population

Asymptomatic pregnant women diagnosed with placenta previa between 28 to 37 weeks' gestation.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Ultrasonographic parameters

    Diagnostic test

    cervical length. placental thickness. distance placental edge from internal os of the cervix

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

maternal bleeding rate

number of attacks of antepartum hemorrhage

Time frame
till delivery

Secondary outcomes

1

Blood transfusion

number of PRBCs

Time frame
till delivery 36 to 37 weeks
2

Emergency Cesarean section

severe antepartum hemorrhage requiring delivery

Time frame
till delivery 36 to 37 weeks
3

Premature delivery

before the planned delivery date (before 37 weeks' gestation)

Time frame
37 week's gestation
4

Need for cesarean hysterectomy

cesarean hysterectomy due to bleeding or placenta accreta spectrum

Time frame
during cesarean section

Other outcomes

Sponsors and contacts

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