About this trial
The aim of this study is to evaluate the effectiveness of ultrasonographic parameters (cervical length, placental thickness and distance placental edge from internal os of the cervix) in predicting the risk of antepartum hemorrhage and emergency cesarean delivery in asymptomatic women with placenta previa.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Asymptomatic women diagnosed with placenta previa according to RCOG (GTG No. 27a, 2018): placenta lies directly over the internal os for pregnancies more than 16 weeks' gestation on transabdominal or transvaginal scanning.
Gestational age between 28 till 37 weeks' gestation (as delivery should be considered between 36 and 37 weeks of gestation for women presenting with uncomplicated placenta previa)
Disqualifiers
Multiple pregnancies.
Threatened preterm labor or preterm rupture of membranes.
History of bleeding in the current pregnancy.
Polyhydraminos (AFI > 25 cm).
Trial population
Asymptomatic pregnant women diagnosed with placenta previa between 28 to 37 weeks' gestation.
Trial design
Cohort
Prospective
Treatments tested in this trial
Ultrasonographic parameters
Diagnostic testcervical length. placental thickness. distance placental edge from internal os of the cervix
Treatment groups
Trial outcomes
Primary outcomes
maternal bleeding rate
number of attacks of antepartum hemorrhage
Secondary outcomes
Blood transfusion
number of PRBCs
Emergency Cesarean section
severe antepartum hemorrhage requiring delivery
Premature delivery
before the planned delivery date (before 37 weeks' gestation)
Need for cesarean hysterectomy
cesarean hysterectomy due to bleeding or placenta accreta spectrum
Sponsors and contacts
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